Select an effect and a duration to create a potion recipe. The essence tier is the higher of the effect tier and the duration's essence tier. The shipped client produces 1 potion per craft, overriding the core default of two. All 36 combinations are listed in the potion recipe catalog.
Effects and durations open through total Alchemy crafts: entry index i requires i × (i + 1) crafts with the default progression multiplier. Existing granted unlocks are retained. The recipe level is the higher effect/duration level and drives craft XP; the client availability check uses the use-based unlock flags rather than treating that number as a new hero-level purchase.
Only 1 potion effect can be active with the shipped defaults. Drinking an already-active effect replaces its remaining timer rather than adding duration. Activating a different effect at the limit removes the oldest effect. One bottle is consumed per drink. Compare potion effects in Potions.